|
Periodontal Pocket
|
0.010 |
Biomarker
|
disease |
BEFREE |
It could be seen that group-I showed statistically significant reduction of deep periodontal pockets and gain in CAL in patients with GAP at 3 months (p < 0.05).
|
31785387 |
2020 |
|
Epilepsies, Partial
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Mutations in the GAP activity toward RAGs 1 (GATOR1) complex genes (DEPDC5, NPRL2 and NPRL3) have been associated with focal epilepsy and focal cortical dysplasia (FCD).
|
31639411 |
2020 |
|
Fleck corneal dystrophy
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Mutations in the GAP activity toward RAGs 1 (GATOR1) complex genes (DEPDC5, NPRL2 and NPRL3) have been associated with focal epilepsy and focal cortical dysplasia (FCD).
|
31639411 |
2020 |
|
Focal cortical dysplasia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Mutations in the GAP activity toward RAGs 1 (GATOR1) complex genes (DEPDC5, NPRL2 and NPRL3) have been associated with focal epilepsy and focal cortical dysplasia (FCD).
|
31639411 |
2020 |
|
Lung Diseases, Interstitial
|
0.060 |
Biomarker
|
group |
BEFREE |
Calibration plots showed the nomogram predicted 1-year mortality better, whilst the ILD-GAP model predicted 2- and 3-year mortality closer to actual mortality rates but underpredicted 1-year mortality.
|
31578022 |
2019 |
|
Malignant neoplasm of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
The ILD-GAP index can predict the prognosis in surgically resected patients with ILD and concomitant lung cancer.
|
31554007 |
2020 |
|
Carcinoma of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
The ILD-GAP index can predict the prognosis in surgically resected patients with ILD and concomitant lung cancer.
|
31554007 |
2020 |
|
Primary malignant neoplasm of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
The ILD-GAP index can predict the prognosis in surgically resected patients with ILD and concomitant lung cancer.
|
31554007 |
2020 |
|
Idiopathic Pulmonary Fibrosis
|
0.090 |
Biomarker
|
disease |
BEFREE |
We aimed to determine the efficacy of LC treatments and the prognosis in LC patients with IPF according to the LC stage and GAP (gender [G], age [A], and two physiology variables [P]) stage.
|
31467375 |
2019 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
|
Colorectal Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
In sum, we reveal a novel TRIM65-GAP-Rho regulatory axis that modulates the actin cytoskeleton and the migration behavior of CRC cells, and the TRIM65-ARHGAP35 interaction might be a valuable therapeutic target in CRC.
|
31332286 |
2019 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study.
|
31268507 |
2019 |
|
Obesity
|
0.020 |
Biomarker
|
disease |
BEFREE |
This suggests a new role for ARHGAP21 in energetic metabolism and prompts us to consider GAP protein members as possible targets for the prevention and treatment of obesity and related diseases.
|
31191459 |
2019 |
|
Idiopathic Pulmonary Fibrosis
|
0.090 |
Biomarker
|
disease |
BEFREE |
Treatment-related complications occurred more frequently in the advanced GAP stage group; advanced GAP stage was the only predictor that exhibited a significant association with the incidence of acute exacerbation of IPF.
|
31186636 |
2019 |
|
Small cell carcinoma of lung
|
0.020 |
Biomarker
|
disease |
BEFREE |
The objective of this study was to investigate survival outcomes and treatment-related complications according to GAP (gender, age, and physiology) stage in patients having SCLC with IPF (SCLC-IPF).
|
31186636 |
2019 |
|
Ketosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Most interestingly, several candidate genes, including previously reported genes (BMP4, HNF4A and APOBR) and newly identified genes (SOCS4, GCH1, ATG14, RGS6, CYP7A1 and MAPK3), are involved in insulin metabolism or lipid metabolism, implicating the contribution of energy-metabolism-associated genes to the genetic basis of KET.
|
31179571 |
2019 |
|
Idiopathic Pulmonary Fibrosis
|
0.090 |
Biomarker
|
disease |
BEFREE |
CONCLUSIONS Spirometry, GAP model, and BAL are helpful to forecast the prognosis of IPF.
|
31166938 |
2019 |
|
Tumor Cell Invasion
|
0.050 |
AlteredExpression
|
phenotype |
BEFREE |
Exogenous expression of wild-type RalGAP, but not the GAP activity-deficient mutant of RalGAP, suppressed migration and invasion of multiple PCa cell lines and was phenocopied by pharmacological inhibition of RalA/B.
|
31058283 |
2019 |
|
Malignant Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
The mechanism of the deceptively simple reaction of guanosine triphosphate (GTP) hydrolysis catalyzed by the cellular protein Ras in complex with the activating protein GAP is an important issue because of the significance of this reaction in cancer research.
|
31041977 |
2019 |
|
Primary malignant neoplasm
|
0.060 |
Biomarker
|
group |
BEFREE |
The mechanism of the deceptively simple reaction of guanosine triphosphate (GTP) hydrolysis catalyzed by the cellular protein Ras in complex with the activating protein GAP is an important issue because of the significance of this reaction in cancer research.
|
31041977 |
2019 |
|
Lung Diseases, Interstitial
|
0.060 |
Biomarker
|
group |
BEFREE |
The ILD-GAP index was used to evaluate mortality risk of baseline ILD.
|
31015884 |
2019 |
|
Lung Diseases, Interstitial
|
0.060 |
Biomarker
|
group |
BEFREE |
The ILD-GAP risk prediction model performs poorly in myositis-associated interstitial lung disease.
|
30961952 |
2019 |
|
Myositis
|
0.010 |
Biomarker
|
disease |
BEFREE |
The ILD-GAP risk prediction model performs poorly in myositis-associated interstitial lung disease.
|
30961952 |
2019 |
|
Back Pain
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
The GAP portal will be designed to be user-friendly and present information on back pain tailored for either patients or physicians in form of brief fact sheets, educative videos, info-graphics, animations and glossaries.
|
30803433 |
2019 |